Visualising the genome: researchers create first 3D structures of active DNA

For the first time, scientists have been able to model the physical structure of mammalian genomes from individual cells, giving us a unique 3D perspective on how DNA packages itself inside our cells.

Through the new technique, scientists can see how the arrangement of cell chromosomes (DNA strands) are designed to keep some cells active or inactive at any one time.

“Knowing where all the genes and control elements are at a given moment will help us understand the molecular mechanisms that control and maintain their expression,” says one of the researchers, Ernest Laue from the University of Cambridge in the UK.

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