A pioneering study to gauge the toxicity of quantum dots in primates has found the tiny crystals to be safe over a one-year period, a hopeful outcome for doctors and scientists seeking new ways to battle diseases like cancer through nanomedicine. The research, which will appear on May 20 in Nature Nanotechnology online, is likely the first to test the safety of quantum dots in primates.
In the study, scientists found that four rhesus monkeys injected with cadmium-selenide quantum dots remained in normal health over 90 days. Blood and biochemical markers stayed in typical ranges, and major organs developed no abnormalities. The animals didn’t lose weight. Two monkeys observed for an additional year also showed no signs of illness.
Quantum dots are tiny luminescent crystals that glow brightly in different colors. Medical researchers are eyeing the crystals for use in image-guided surgery, light-activated therapies and sensitive diagnostic tests. Cadmium selenide quantum dots are among the most studied, with potential applications not only in medicine, but as components of solar cells, quantum computers, light-emitting diodes and more.