The fascinating life cycle of the Sheep Liver Fluke

Fasciola hepatica, also known as the common liver fluke or sheep liver fluke, is a parasitic flatworm of the class Trematoda, phylum Platyhelminthes that infects the livers of various mammals, including humans. The disease caused by the fluke is called fascioliasis (also known as fasciolosis). F. hepatica is distributed worldwide, and causes great economic losses in sheep and cattle.

To complete its life cycle, F. hepatica requires a freshwater snail as an intermediate host, such as Galba truncatula, in which the parasite can reproduce asexually.

From the snail, minute cercariae emerge and swim through pools of water in pasture, and encyst as metacercariae on near-by vegetation. From here, the metacercariae are ingested by the ruminant, or in some cases, by humans eating uncooked foods such as watercress. Contact with low pH in the stomach causes the early immature juvenile to begin the process of excystment. In the duodenum, the parasite breaks free of the metacercariae and burrows through the intestinal lining into the peritoneal cavity. The newly excysted juvenile does not feed at this stage, but once it finds the liver parenchyma after a period of days, feeding will start. This immature stage in the liver tissue is the pathogenic stage, causing anaemia and clinical signs sometimes observed in infected animals. The parasite browses on liver tissue for a period of up to six weeks, and eventually finds its way to the bile duct, where it matures into an adult and begins to produce eggs. Up to 25,000 eggs per day per fluke can be produced, and in a light infection, up to 500,000 eggs per day can be deposited onto pasture by a single sheep.

via Fasciola hepatica 

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2 Responses to The fascinating life cycle of the Sheep Liver Fluke

  1. alfy says:

    Again, thanks for doing this. As an A Level student in the fifties Fasciola was part of the syllabus so I knew it pretty well. At degree level we studied other fluke parasites. I didn’t want to pull rank on Phil but I knew that ants don’t figure in the Fasciola cycle, although there may be some unusual fluke cycles which do, but I doubt it. When particular groups of parasites come up with a good game plan they generally stick to it. The cycle mammal to mollusc and back again seems to suit them.
    I must have a look at some of the more weird cycles again, because now we have hit on this topic it could make for some interesting posts.

  2. Phil Krause says:

    But where’s the ant?

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